EVERYONE WANTS TO BELIEVE THAT THE $1 BIOTECH STOCK THEY OWN TODAY
WILL BE A $10 STOCK TOMORROW. HUMAN GENOME IS ONE OF THE GREAT
SPECULATIVE SUCCESS STORIES THIS YEAR. SO IS VANDA PHARMACEUTICALS (VNDA
QUOTE) AND EVEN, DARE I SAY IT, CELL THERAPEUTICS. CARL WILLIAM
BROWN
BANK OF AMERICA CORPORATION
(Public, NYSE:BAC)
http://www.bankofamerica.com
Bank of America Corporation (Bank of America) is a bank holding
company and a financial holding company. Through its banking
subsidiaries and various non-banking subsidiaries throughout the
United States and in selected international markets, it provides a
diversified range of banking and non-banking financial services and
products through three business segments: Global Consumer and Small
Business Banking, Global Corporate and Investment Banking and Global
Wealth and Investment Management. Bank of America operates in 50
states, the District of Columbia and more than 40 foreign countries.
Bank of America has 6,100 banking centers, approximately 18,700
automated teller machines (ATMs), nationwide call centers, and
online and mobile banking platforms. On January 1, 2009, Bank of
America announced the purchase of Merrill Lynch & Co., Inc. On July
1, 2008, Bank of America completed the acquisition of Countrywide
Financial Corporation.
CITIGROUP INC. (Public, NYSE:C)
http://www.citigroup.com
Citigroup Inc. (Citigroup) is a global diversified financial
services holding company. The Company is engaged in providing a
range of financial services to consumers and corporate customers. As
of May 4, 2009, Citigroup had more than 200 million customer
accounts and did business in more than 140 countries. Through its
two operating units, Citicorp and Citi Holdings, Citigroup provides
consumers, corporations, governments and institutions with a range
of financial products and services, including consumer banking and
credit, corporate and investment banking, securities brokerage, and
wealth management.In August 2009, the Company sold three credit card
portfolios.
CELL THERAPEUTICS Inc. (NASDAQ:CTIC)
http://www.celltherapeutics.com
Cell Therapeutics, Inc. (Cell Therapeutics) develops, acquires and
commercializes treatments for cancer. The Company’s research,
development, acquisition and in-licensing activities concentrate on
identifying and developing new, less toxic and effective ways to
treat cancer. Cell Therapeutics is developing pixantrone (BBR 2778),
a deoxyribonucleic acid (DNA) major groove binder with an
aza-anthracenedione molecular structure, differentiating it from
anthracycline chemotherapy agents. A new chemical compound for the
treatment of non-Hodgkin’s lymphoma (NHL), and various other
hematologic malignancies, solid tumors, and immunological disorders,
pixantrone is being developed to improve activity and safety in
treating cancers treated with the anthracycline family of
anti-cancer agents. It is developing OPAXIO (paclitaxel poliglumex),
which was previously referred to as XYOTAX, for the treatment of
non-small cell lung cancer (NSCLC), and ovarian cancer.
NOVAVAX, INC. (Public, NASDAQ:NVAX)
http://www.novavax.com/
Novavax, Inc. (Novavax) is a clinical-stage biopharmaceutical
company focused on creating differentiated, value-added vaccines
that improve upon preventive options for a range of infectious
diseases. These vaccines leverage its virus-like particle (VLP)
platform technology coupled with a disposable production technology.
VLPs are genetically engineered three-dimensional nanostructures,
which incorporate immunologically important lipids and recombinant
proteins. Novavax’s VLPs resemble the virus but lack the genetic
material to replicate the virus. Its production technology uses
insect cells rather than chicken eggs or mammalian cells. The
Company’s product targets include vaccines against the H5N1 and
other subtypes of avian influenza with pandemic potential, human
seasonal influenza, Varicella Zoster, which causes shingles, and
respiratory syncytial virus (RSV). This RSV vaccine was announced on
October 30, 2008.
BRISTOL MYERS SQUIBB CO. (Public, NYSE:BMY)
http://www.bms.com
Bristol-Myers Squibb Company (BMS) is engaged in the discovery,
development, licensing, manufacturing, marketing, distribution and
sale of pharmaceutical and nutritional products. The Company had two
segments: Pharmaceuticals and Nutritionals. The Pharmaceuticals
segment is made up of the global pharmaceutical and international
consumer medicines business. The Nutritionals segment consists of
Mead Johnson Nutritionals (Mead Johnson), primarily an infant
formula and children’s nutritionals business. In June 2008, BMS
acquired Kosan Biosciences, Inc., a developer of oncology products.
In August 2008, the Company completed the divestiture of its
ConvaTec business to Cidron Healthcare Limited, an affiliate of
Nordic Capital Fund VII and Avista. In December 2008, BMS completed
the sale of its brand business in Egypt to GlaxoSmithKline. In July
2009, the Company's branded generics business, which comprises a
portfolio of 13 branded pharmaceuticals was acquired by
GlaxoSmithKline plc.
IMMUNOMEDICS, INC. (Public, NASDAQ:IMMU)
http://www.immunomedics.com/
Immunomedics, Inc. is a New Jersey-based biopharmaceutical company
primarily focused on the development of monoclonal, antibody-based
products for the targeted treatment of cancer, autoimmune and other
serious diseases. It has developed a number of advanced technologies
that allow it to create humanized antibodies that can be used either
alone in unlabeled or naked form, or conjugated with radioactive
isotopes, chemotherapeutics or toxins, in each case to create
targeted agents. It has licensed its product candidate epratuzumab,
to UCB S.A. (UCB), for the treatment of all autoimmune disease
indications. Epratuzumab’s advanced clinical testing is for the
treatment of systemic lupus erythematosus (SLE), and in
non-Hodgkin’s lymphoma (NHL). It has retained the rights for
epratuzumab in oncology indications, subject to UCB’s buy-in option,
and is advancing trials in lymphoma and in childhood acute
lymphoblastic leukemia (ALL), in cooperation with National Cancer
Institute Study Groups.
ANTIGENICS, INC. (Public, NASDAQ:AGEN)
http://www.antigenics.com
Antigenics Inc. (Antigenics), is a biotechnology company focused on
developing and commercializing technologies to treat cancers and
infectious diseases, primarily based on immunological approaches.
The Company’s principal product candidate is Oncophage (vitespen), a
patient-specific therapeutic cancer vaccine. Oncophage has been
tested in Phase III clinical trials for the treatment of renal cell
carcinoma, the common type of kidney cancer, and for the treatment
of metastatic melanoma. It has also been tested in Phase I and Phase
II clinical trials in a range of indications and is in a Phase II
clinical trial in recurrent glioma, a type of brain cancer. The
Company’s product candidate portfolio also includes QS-21 Stimulon
adjuvant (QS-21), which is used in numerous vaccines, AG-707, a
therapeutic vaccine program for the treatment of genital herpes and
Aroplatin, a liposomal chemotherapeutic for the treatment of solid
malignancies and B-cell lymphomas
SPECTRUM PHARMACEUTICALS, INC. (Public,
NASDAQ:SPPI)
http://www.spectrumpharm.com
Spectrum Pharmaceuticals, Inc. ( Spectrum) is a commercial stage
biopharmaceutical company, engaged in developing and commercializing
therapies with a focus primarily in the areas of hematology-oncology
and urology. The Company’s product is apaziquone (formerly EOquin),
which is in two Phase 3 clinical trials for non-muscle invasive
bladder cancer under a collaboration with Allergan Inc. Another drug,
ozarelix is in a Phase 2 clinical trial for benign prostatic
hypertrophy (BPH). On December 15, 2008, Spectrum and Cell
Therapeutics, Inc. (CTI) partnered to form a joint venture, RIT
Oncology, LLC (RIT), to develop Zevalin ([90Y]-ibritumomab tiuxetan)
in the United States. Its subsidiaries include OncoRx Pharma Private
Limited, Spectrum Pharmaceuticals GmbH, RIT Oncology, LLC and
Spectrum Pharma Canada. During the year ended December 31, 2008, the
Company dissolved NeoJB LLC.
BRAINSTORM CELL THERAPEUTICS INC
(Public, OTC:BCLI)
http://www.brainstorm-cell.com
Brainstorm Cell Therapeutics Inc. (Brainstorm) is a
development-stage company. The Company is engaged in developing stem
cell therapeutic products based on technologies enabling the
in-vitro differentiation of bone marrow stem cells to neural-like
cells. The Company focuses on utilizing the patient’s own bone
marrow stem cells to generate neurotrophic factors (NTF) cells that
may provide treatment for amyotrophic lateral sclerosis (ALS),
parkinson’s disease (PD) and spinal cord injury. The Company’s
technology is based on the NurOwn products, an autologous cell
therapeutic modality, consisting of the extraction of the patient
bone marrow, processed into neuronal-like cells and re-implanted
into the patient’s muscles or brain.
HUMAN GENOME SCIENCES (Public, NASDAQ:HGSI)
http://www.hgsi.com
Human Genome Sciences (HGS)is a commercially focused
biopharmaceutical company. The Company has three products in
late-stage clinical development: Albuferon for chronic hepatitis C,
LymphoStat-B for systemic lupus erythematosus and ABthraxtm for
inhalation anthrax. Albuferon and LymphoStat-B are progressing
toward commercialization. In December 2008, the Company reported
that Albuferon met its primary endpoint in the first of two Phase
III clinical trials in chronic hepatitis C. HGS also has several
drugs in earlier stages of clinical development for the treatment of
cancer, led by its TRAIL receptor antibody HGS-ETR1 and a
small-molecule antagonist of IAP (inhibitor of apoptosis) proteins.
OCULUS INNOVATIVE SCIENCES, INC.
(Public, NASDAQ:OCLS)
http://www.oculusis.com
Oculus Innovative Sciences, Inc. is a biopharmaceutical company that
develops, manufactures and markets a family of products, based on
its platform technology called Microcyn, intended to help prevent
and treat infections in chronic and acute wounds. Microcyn is a
non-irritating oxychlorine compound designed to treat a range of
pathogens, including viruses, fungi, spores and antibiotic-resistant
strains of bacteria, such as Methicillin-resistant Staphylococcus
aureus (MRSA), and Vancomycin-resistant Enterococcus (VRE), in
wounds. Its device product is cleared for sale in the United States
as a 510(k) medical device for wound cleaning, debridement,
lubricating, moistening and dressing; is a device under Conformite
Europeenne (CE) Mark in Europe; is approved by the State Food and
Drug Administration (SFDA), in China as a technology that reduces
the propagation of microbes in wounds and creates a moist
environment for wound healing, and is approved as a drug in India
and Mexico.
UNICREDIT (BIT:UCG)
http://www.unicreditgroup.eu
UniCredit SpA is Italy-based holding company engaged in the
financial sector. The Company’s division model is based on four
business areas: Network Management Divisions; Centralized Product,
Key Business Functions; Global Service Factories, and Multi-Local
Approach. The Network Management Divisions consist of the retail
markets, corporate and private banking. Its Centralized Product, Key
Business Functions include markets and investment banking, asset
management, leasing, household financing, global transaction banking,
and retail marketing and segments. The Global Service Factories
provide, among others back office, credit collection, procurement
services and real estate for supplying network management divisions
and product factories with specialized services. The Multi-Local
Approach focuses on the relations between local banks and clients.
It operates in 22 European countries through the local banks, and it
also has offices and representatives in Asia and the United States.
ARENA AGROINDUSTRIE ALIMENTARI SpA
(Public, BIT:ARE)
http://www.arenaholding.it
ARENA Agroindustrie Alimentari SpA is an Italy-based food producer
for large retailers. Arena Agroindustrie Alimentari SpA is active in
the food sector, mainly in the poultry sector. It concentrates its
activity on the marketing of fresh poultry products. The Company has
four subsidiaries: Arena Alimentari Freschi SpA, Co dis al Srl,
Gelus NV and Interfin SpA.
AEDES SpA (Public, BIT:AE)
http://www.aedes-immobiliare.com
Aedes SpA is an Italy-based real estate company. It is a co-investor
and management company focused on two areas of business: property
services and co-investments. The property services business includes
management of property funds, carried out through two savings
management companies: Aedes BPM Real Estate SGR SpA and Aedes Value
Added SGR, and provision of property services, carried out through
five companies: Aedes Servizi SpA, Aedes Project Srl, Aedes Agency
Srl, Agora Srl and Unicenter Srl. It also provides a tailor-made
management service at every stage of any real estate project, with
an integrated range of services: asset management, fund management,
advisory, development, project management, planning engineering,
intermediation, shopping mall management and financial,
administrative and corporate government services.
GABETTI PROPERTY SOLUTIONS SpA (Public BIT:GAB)
http://www.gabetti.it/
Gabetti Property Solutions SpA, is a real estate holding company
engaged in the planning, development, construction, management, sale
and leasing of real estate properties in Italy. The Company operates
through four main business lines: Agency, with Gabetti Agency SpA
and Tree Real Estate Srl, consisting in direct real estate agencies,
for the corporate, fractioning, and luxury sectors, and in a
franchising network for the retail sector. Finance, with Tree
Finance Srl, for credit brokerage services in the retail, corporate,
and insurance sectors; Technical Services, with the Abaco group and
Patrigest SpA, for services in the due diligence, property and
facility management, consulting & advisory, ITC services B2B, energy
efficiency certifications, real estate valuation and advisory,
feasibility studies, and market analysis sectors; and Investment &
Property, with La Gaiana SpA, for real estate trading and
development investment activities, in Italy and abroad.
GEMINA SpA (Public, BIT:GEM)
http://www.gemina.it/
GEMINA Generale Mobiliare Interessenze Azionarie SpA (GEMINA) is an
Italy-based investment holding company. The Company’s activities are
structured of investments in the companies from four segments:
airport activities; electric energy; air traffic control system, and
others. In the airport activities segment, GEMINA is present by
direct interests held in Aeroporti di Roma SpA (95.76%) , which
manages airports in Rome. In the electric energy sector, it operates
through the interests held in Sistemi di Energia SpA (45.55%). In
the air traffic control system segment, the Company is active
through interests held in S.I.T.T.I. SpA (40%). The company is
present also in other sector through interests held in Pentar SpA
(20.35%).
PRAMAC S.p.A. (Public, BIT:PRA)
http://www.pramac.com
Pramac SpA is an Italy-based company engaged in the manufacturing of
the power generation equipment, materials handling equipment and
photovoltaic components. The Company divides its activities into
three business sectors: Power, which comprises generators for
electric power, including low voltage portable generators and medium
and high voltage generators; Handling, which includes the
manufacturing and distribution of the machinery for handling
logistic; and Ecopower for the photovoltaic components. The Company
has six production plants in Italy, Spain, France, China, the USA
and Switzerland. It operates worldwide through the distribution
network of subsidiaries among which are: Pramac France SAS, Pramac
Lifter GmbH, Pramac Group Scandinavia Aps, Pramac Lifter Afrique
Trading Sarl, Masons Power Generators Ltd and Pramac Swiss SA, among
others.
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